Article

Pneumolysin-dependent and independent non-canonical autophagy processes mediate host defense against pneumococcal infection

2025-02-15

Abstract excerpt

Streptococcus pneumoniae is an opportunistic pathogen responsible for life-threatening diseases including pneumonia and meningitis. The host defense against pneumococci relies heavily on macrophages, which can effectively internalize and degrade bacteria. Recent studies have implicated both canonical and non-canonical autophagy-related processes in bacterial clearance, but the precise pathways mediating defense ag...

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Literature Corpus work: 792c3174-03b5-567f-8181-305d913d8e4c
DOI: 10.1101/2025.02.11.637156

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