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LAPped in Proof: LC3‐Associated Phagocytosis and the Arms Race Against Bacterial Pathogens

3 Jan 2022

Abstract excerpt

Cells of the innate immune system continuously patrol the extracellular environment for potential microbial threats that are to be neutralized by phagocytosis and delivery to lysosomes. In addition, phagocytes employ autophagy as an innate immune mechanism against pathogens that succeed to escape the phagolysosomal pathway and invade the cytosol. In recent years, LC3-associated phagocytosis (LAP) has emerged as...

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PMID: 35047422
DOI: 10.3389/fcimb.2021.809121

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