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LC3-Associated Phagocytosis in Bacterial Infection

30 Jul 2022

Abstract excerpt

LC3-associated phagocytosis (LAP) is a noncanonical autophagy process reported in recent years and is one of the effective mechanisms of host defense against bacterial infection. During LAP, bacteria are recognized by pattern recognition receptors (PRRs), enter the body, and then recruit LC3 onto a single-membrane phagosome to form a LAPosome. LC3 conjugation can promote the fusion of the LAPosomes with...

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PMID: 36014984
DOI: 10.3390/pathogens11080863

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