Article
Pathway analysis shows association between FGFBP1 and hypertension.
Journal of the American Society of Nephrology : JASN - 1 May 2011
Tomaszewski Maciej, Charchar Fadi J, Nelson Christopher P, Barnes Timothy, Denniff Matthew, Kaiser Michael, Debiec Radoslaw, Christofidou Paraskevi, Rafelt Suzanne, van der Harst Pim, Wang William Y S, Maric Christine, Zukowska-Szczechowska Ewa, Samani Nilesh J
Abstract excerpt
Variants in the gene encoding fibroblast growth factor 1 (FGF1) co-segregate with familial susceptibility to hypertension, and glomerular upregulation of FGF1 associates with hypertension. To investigate whether variants in other members of the FGF signaling pathway may also associate with hypertension, we genotyped 629 subjects from 207 Polish families with hypertension for 79 single nucleotide polymorphisms in...
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