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Article

Isolation and characterization of a novel class II histone deacetylase, HDAC10.

The Journal of biological chemistry - 22 Feb 2002

Fischer Denise D, Cai Richard, Bhatia Umesh, Asselbergs Fred A M, Song Chuanzheng, Terry Robert, Trogani Nancy, Widmer Roland, Atadja Peter, Cohen Dalia

Abstract excerpt

A novel histone deacetylase, HDAC10, was isolated from a mixed tissue human cDNA library. HDAC10 was classified as a class II subfamily member based upon similarity to HDAC6. The genomic structure of HDAC10 was found to consist of 20 exons. HDAC10 has two sequence variants, HDAC10v1 and HDAC10v2, and two transcripts were detectable by Northern blot analysis. HDAC10v1 and HDAC10v2 were found to be identical...

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Share to Catalytic Domain
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Library

Share to Histone Deacetylases

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Share to Sequence Homology, Amino Acid

Share to Sequence Homology, Nucleic Acid

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 11739383
DOI: 10.1074/jbc.M108055200

Genes

HDAC10
HDAC2
HDAC6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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