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Article

A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia.

EMBO molecular medicine - 1 Jun 2011

Grube Sabrina, Gerchen Martin F, Adamcio Bartosz, Pardo Luis A, Martin Sabine, Malzahn Dörthe, Papiol Sergi, Begemann Martin, Ribbe Katja, Friedrichs Heidi, Radyushkin Konstantin A, Müller Michael, Benseler Fritz, Riggert Joachim, Falkai Peter, Bickeböller Heike, Nave Klaus-Armin, Brose Nils, Stühmer Walter, Ehrenreich Hannelore

Abstract excerpt

KCNN3, encoding the small conductance calcium-activated potassium channel SK3, harbours a polymorphic CAG repeat in the amino-terminal coding region with yet unproven function. Hypothesizing that KCNN3 genotypes do not influence susceptibility to schizophrenia but modify its phenotype, we explored their contribution to specific schizophrenic symptoms. Using the Göttingen Research Association for Schizophrenia...

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Identifiers

PMID: 21433290
DOI: 10.1002/emmm.201100135
PMCID: PMC3377084

Genes

KCNN3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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