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Article

Variations in folate pathway genes are associated with unexplained female infertility.

Fertility and sterility - 1 Jun 2010

Altmäe Signe, Stavreus-Evers Anneli, Ruiz Jonatan R, Laanpere Margit, Syvänen Tiina, Yngve Agneta, Salumets Andres, Nilsson Torbjörn K

Abstract excerpt

OBJECTIVE: To investigate associations between folate-metabolizing gene variations, folate status, and unexplained female infertility. DESIGN: An association study. SETTING: Hospital-based IVF unit and university-affiliated reproductive research laboratories. PATIENT(S): Seventy-one female patients with unexplained infertility. INTERVENTION(S): Blood samples for polymorphism genotyping and homocysteine, vitamin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Receptors, Cell Surface

Share to Reduced Folate Carrier Protein

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Source

Identifiers

PMID: 19324355
DOI: 10.1016/j.fertnstert.2009.02.025

Genes

MTHFR
CTH
FOLR1
TCN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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