Article
T677T Methylenetetrahydrofolate Reductase Single Nucleotide Polymorphisms Increased Prevalence in a Subgroup of Infertile Patients with Endometriosis.
Journal of women's health (2002) - 1 Oct 2022
Clément Patrice, Alvarez Silvia, Jacquesson-Fournols Laetitia, Cornet Dominique, Clément Arthur, Brack Michel, Lalau-Keraly Marc, Delafontaine Didier, Cohen Marc, Menezo Yves
Abstract excerpt
Background: Approximately 10% (190 million) of women worldwide are affected by endometriosis, ectopic deposits of endometrial tissue that create a major source of pain that affects lifestyle and reproductive function. The pathogenesis of endometriosis is an estrogen-dependent inflammatory process, influenced/catalyzed by oxidative stress and consequently defective methylation, with biochemical features centered...
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