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Article

Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians.

Retrovirology - 23 Mar 2011

Malhotra Rakhi, Hu Liangyuan, Song Wei, Brill Ilene, Mulenga Joseph, Allen Susan, Hunter Eric, Shrestha Sadeep, Tang Jianming, Kaslow Richard A

Abstract excerpt

BACKGROUND: Polymorphisms in chemokine (C-C motif) receptors 2 and 5 genes (CCR2 and CCR5) have been associated with HIV-1 infection and disease progression. We investigated the impact of CCR2-CCR5 haplotypes on HIV-1 viral load (VL) and heterosexual transmission in an African cohort. Between 1995 and 2006, cohabiting Zambian couples discordant for HIV-1 (index seropositive and HIV-1 exposed seronegative {HESN})...

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Source

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Identifiers

PMID: 21429204
DOI: 10.1186/1742-4690-8-22
PMCID: PMC3075214

Genes

CCR2
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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