Article
A comparison of the effects of single-base and triple-base changes in the integrase arm-type binding sites on the site-specific recombination of bacteriophage lambda.
Nucleic acids research - 11 Jul 1990
Numrych T E, Gumport R I, Gardner J F
Abstract excerpt
Triple-base changes were made in each of the five Integrase (Int) arm-type binding sites of bacteriophage lambda. These triple changes, called ten mutants, were compared with single-base changes (hen mutants) for their effects on integrative and excisive recombination. The presence of ten or hen...
Topics
- Attachment Sites, Microbiological
- Bacteriophage lambda
- Base Composition
- Base Sequence
- Binding Sites
- DNA Nucleotidyltransferases
- Integrases
- Lysogeny
- Molecular Sequence Data
- Mutation
- Recombination, Genetic