Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A comparison of the effects of single-base and triple-base changes in the integrase arm-type binding sites on the site-specific recombination of bacteriophage lambda.

Nucleic acids research - 11 Jul 1990

Numrych T E, Gumport R I, Gardner J F

Abstract excerpt

Triple-base changes were made in each of the five Integrase (Int) arm-type binding sites of bacteriophage lambda. These triple changes, called ten mutants, were compared with single-base changes (hen mutants) for their effects on integrative and excisive recombination. The presence of ten or hen mutations in the P1, P'2, or P'3 sites inhibited integration, but the ten P'3 mutant was 10-fold more defective than...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophage lambda
Share to Base Composition

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Base Sequence

Share to Binding Sites

Share to DNA Nucleotidyltransferases

Share to Molecular Sequence Data

Share to Mutation

Share to Recombination, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 2142765
DOI: 10.1093/nar/18.13.3953
PMCID: PMC331098

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A comparison of the effects of single-base and triple-base changes in the integrase arm-type binding sites on the site-specific recombination of bacteriophage lambda.PMID 2142765Read ↗

Defining the structural and functional roles of the carboxyl region of the bacteriophage lambda excisionase (Xis) protein.Semantic proximity Read ↗

Mutations at residues 282, 286, and 293 of phage lambda integrase exert pathway-specific effects on synapsis and catalysis in recombination.Semantic proximity Read ↗

Genetic analysis of bacteriophage lambda integrase interactions with arm-type attachment site sequences.Semantic proximity Read ↗

Analysis of insertion into secondary attachment sites by phage lambda and by int mutants with altered recombination specificity.Semantic proximity Read ↗

Genetic analysis of second-site revertants of bacteriophage lambda integrase mutants.Semantic proximity Read ↗

The effect of mutations in the Xis-binding sites on site-specific recombination in coliphage HK022.Semantic proximity Read ↗

Alterations in the directionality of lambda site-specific recombination catalyzed by mutant integrases in vivo.Semantic proximity Read ↗

Specificity in DNA recognition by phage integrases.Semantic proximity Read ↗

Effects of dimer interface mutations in Hin recombinase on DNA binding and recombination.Semantic proximity Read ↗

A motif in the C-terminal domain of phiC31 integrase controls the directionality of recombination.Semantic proximity Read ↗

Gin mutants that can be suppressed by a Fis-independent mutation.Semantic proximity Read ↗

Role of secondary attachment sites in changing the specificity of site-specific recombination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.