Mutation of the human FMS gene (M-CSF receptor) in myelodysplastic syndromes and acute myeloid leukemia.

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Article

Mutation of the human FMS gene (M-CSF receptor) in myelodysplastic syndromes and acute myeloid leukemia.

Leukemia - 1 Jul 1990

Tobal K, Pagliuca A, Bhatt B, Bailey N, Layton D M, Mufti G J

Abstract excerpt

We studied 41 patients with myelodysplastic syndromes or acute myeloid leukemia to assess the presence of point mutations in the human FMS gene (M-CSF receptor). Using the polymerase chain reaction and hybridization of oligonucleotide probes to the amplified sequences, we have detected mutations...

Topics

Alleles
Base Sequence
Codon
Humans
Leukemia, Myeloid, Acute
Molecular Sequence Data
Mutation
Myelodysplastic Syndromes
Nucleic Acid Hybridization
Oligonucleotides
Polymerase Chain Reaction
Proto-Oncogene Proteins
Receptor, Macrophage Colony-Stimulating Factor

Source

Open in PubMed

Identifiers

PMID: 2142747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2142747-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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