FMS mutations in myelodysplastic, leukemic, and normal subjects.

doi:10.1073/pnas.87.4.1377

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Article

FMS mutations in myelodysplastic, leukemic, and normal subjects.

Proceedings of the National Academy of Sciences of the United States of America - 1 Feb 1990

Ridge S A, Worwood M, Oscier D, Jacobs A, Padua R A

Abstract excerpt

The FMS gene encodes the functional cell surface receptor for colony-stimulating factor 1, the macrophage- and monocyte-specific growth factor. Codons 969 and 301 have been identified as potentially involved in promoting the transforming activity of FMS. Mutations at codon 301 are believed to lea...

Topics

Anemia
Anemia, Sideroblastic
Base Sequence
Bone Marrow
Cloning, Molecular
Codon
Colony-Stimulating Factors
DNA
Genes
Humans
Leukemia, Myeloid, Acute
Leukemia, Myelomonocytic, Chronic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Macrophage Colony-Stimulating Factor

Molecular Sequence Data

Mutation

Myelodysplastic Syndromes

Oligonucleotide Probes

Plasmids

Source

Open in PubMed Open full text

Identifiers

PMID: 2406720
DOI: 10.1073/pnas.87.4.1377
PMCID: PMC53478

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2406720-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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