Article
Increased heterozygosity in low-pass sequencing data allows identification of blood chimeras in cattle.
Animal genetics - 1 Oct 2023
Lindtke Dorothea, Seefried Franz R, Drögemüller Cord, Neuditschko Markus
Abstract excerpt
In about 90% of multiple pregnancies in cattle, shared blood circulation between fetuses leads to genetic chimerism in peripheral blood and can reduce reproductive performance in heterosexual co-twins. However, the early detection of heterosexual chimeras requires specialized tests. Here, we used low-pass sequencing data with a median coverage of 0.64× generated from blood samples of 322 F1 crosses between beef...
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