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Genome wide profiling of altered gene expression in the neocortex of Alzheimer's disease

23 Nov 2009

Abstract excerpt

Alzheimer's disease (AD) is characterized by a complex neurodegenerative process affecting multiple genes and proteins in the neocortex, many of which have not been well-studied. In this study, we investigated genome-wide gene alterations in the temporal cortex of a well-characterized cohort of AD patients using a recently developed microarray platform, and compared some of the transcript changes with...

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PMID: 19937809
DOI: 10.1002/jnr.22290

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