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Senescence-related genes and proteins in the development of Alzheimer’s disease: evidence from transcriptomic and Mendelian randomization analysis

2 Aug 2024

Abstract excerpt

Purpose Alzheimer’s disease (AD) is a common neurodegenerative disease, which can lead to cognitive impairment and dementia. Since AD is tightly associated with aging and cellular senescence, objective of this study was to investigate the association between senescence-related genes and proteins (SRGs and SRPs) and the development of AD. Design The whole study was based on transcriptomic analysis of control and...

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Share to Epigenetics and DNA Methylation
Share to Genetics, Aging, and Longevity in Model Organisms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39156738
DOI: 10.3389/fnagi.2024.1423725

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