Secondary CD8+ T-cell responses are controlled by systemic inflammation.

Abstract excerpt

Repeated infections and experimental prime-boost regimens frequently result in the generation of secondary (2°) CD8(+) T-cell responses. In contrast to primary (1°) CD8(+) T cells, the parameters that influence the abundance and phenotype of 2° effector and memory CD8(+) T-cell populations are largely unknown. Here, we analyze the impact of different booster infections, Ag curtailment, and systemic inflammation...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Ampicillin
• Share to Immunization, Secondary
• Share to Immunologic Memory