Article
Functional models for congenital anomalies of the kidney and urinary tract.
Nephron - 1 Jan 2015
van de Hoek Glenn, Nicolaou Nayia, Giles Rachel H, Knoers Nine V A M, Renkema Kirsten Y, Bongers Ernie M H F
Abstract excerpt
Congenital anomalies of the kidney and urinary tract (CAKUT) constitute one of the most common developmental diseases in humans; however, the cause for most patients remains unknown. Efforts to identify novel genetic causes for CAKUT through next-generation sequencing techniques have led to the discovery of new genes and risk factors. Concomitantly, these same efforts have generated large gene candidate lists...
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