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Article

The C3H/HeJ inbred mouse is a model of vesico-ureteric reflux with a susceptibility locus on chromosome 12.

Kidney international - 1 Aug 2010

Murawski Inga J, Maina Rita W, Malo Danielle, Guay-Woodford Lisa M, Gros Philippe, Fujiwara Mary, Morgan Kenneth, Gupta Indra R

Abstract excerpt

Vesico-ureteric reflux is the most common congenital anomaly of the urinary tract, characterized by a defective uretero-vesical junction with retrograde urine flow from the bladder toward the kidneys. Because there is strong evidence for a genetic basis for some cases of vesico-ureteric reflux, we screened 11 inbred mouse strains for reflux and kidney size and identified one strain, C3H/HeJ, that has a 100...

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Identifiers

PMID: 20407478
DOI: 10.1038/ki.2010.110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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