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Article

Combined RET and Ki-67 assessment in sporadic medullary thyroid carcinoma: a useful tool for patient risk stratification.

European journal of endocrinology - 1 Jun 2011

Mian Caterina, Pennelli Gianmaria, Barollo Susi, Cavedon Elisabetta, Nacamulli Davide, Vianello Federica, Negro Isabella, Pozza Giulia, Boschin Isabella Merante, Pelizzo Maria Rosa, Rugge Massimo, Mantero Franco, Girelli Maria Elisa, Opocher Giuseppe

Abstract excerpt

OBJECTIVE: Medullary thyroid carcinoma (MTC) derives from the parafollicular C cells, being sporadic in 75% of cases and familial in 25%, due to RET proto-oncogene germinal mutations. In sporadic forms, stage at diagnosis is the most important negative prognostic factor. The aim of this study was to evaluate the prognostic impact of molecular and immunohistochemical markers in sporadic MTC. DESIGN AND METHODS: We...

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Identifiers

PMID: 21422198
DOI: 10.1530/EJE-11-0079

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RET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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