Article
Effects of 34 risk loci for type 2 diabetes or hyperglycemia on lipoprotein subclasses and their composition in 6,580 nondiabetic Finnish men.
Diabetes - 1 May 2011
Stančáková Alena, Paananen Jussi, Soininen Pasi, Kangas Antti J, Bonnycastle Lori L, Morken Mario A, Collins Francis S, Jackson Anne U, Boehnke Michael L, Kuusisto Johanna, Ala-Korpela Mika, Laakso Markku
Abstract excerpt
OBJECTIVE: We investigated the effects of 34 genetic risk variants for hyperglycemia/type 2 diabetes on lipoprotein subclasses and particle composition in a large population-based cohort. RESEARCH DESIGN AND METHODS: The study included 6,580 nondiabetic Finnish men from the population-based Metabolic Syndrome in Men (METSIM) study (aged 57 ± 7 years; BMI 26.8 ± 3.7 kg/m(2)). Genotyping of 34 single nucleotide...
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