Article
Distinct response of yeast ribosomes to a miscoding event during translation.
RNA (New York, N.Y.) - 1 May 2011
Eyler Daniel E, Green Rachel
Abstract excerpt
Numerous mechanisms have evolved to control the accuracy of translation, including a recently discovered retrospective quality control mechanism in bacteria. This quality control mechanism is sensitive to perturbations in the codon:anticodon interaction in the P site of the ribosome that trigger a dramatic loss of fidelity in subsequent tRNA and release factor selection events in the A site. These events...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
