Article
Association between the ROBO1 gene and body mass index in patients using antipsychotics.
Psychiatric genetics - 1 Aug 2011
Vehof Jelle, Al Hadithy Asmar F Y, Burger Huibert, Snieder Harold, Risselada Arne J, Wilffert Bob, Cohen Dan, Arends Johan, Wiersma Durk, Mulder Hans, Bruggeman Richard
Abstract excerpt
BACKGROUND: Weight gain is one of the major problems in patients using antipsychotic medication, leading to relevant morbidities and reduced compliance to pharmacotherapy. Recently, an association has been reported between a single nucleotide polymorphism (rs1455832) of the roundabout axon guidance receptor, homolog 1 (ROBO1) gene and body mass index (BMI) in persons younger than 30 years. The aim of this study...
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