Article
Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients.
Arthritis research & therapy - 1 Jan 2006
Pierer Matthias, Kaltenhäuser Sylke, Arnold Sybille, Wahle Matthias, Baerwald Christoph, Häntzschel Holm, Wagner Ulf
Abstract excerpt
The functional single-nucleotide polymorphism (SNP) of the gene PTPN22 is a susceptibility locus for rheumatoid arthritis (RA). The study presented here describes the association of the PTPN22 1858T allele with RA in a German patient cohort; 390 patients with RA and 349 controls were enrolled in...
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