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Article

Nuclear mitochondrial DNA activates replication in Saccharomyces cerevisiae.

PloS one - 8 Mar 2011

Chatre Laurent, Ricchetti Miria

Abstract excerpt

The nuclear genome of eukaryotes is colonized by DNA fragments of mitochondrial origin, called NUMTs. These insertions have been associated with a variety of germ-line diseases in humans. The significance of this uptake of potentially dangerous sequences into the nuclear genome is unclear. Here we provide functional evidence that sequences of mitochondrial origin promote nuclear DNA replication in Saccharomyces...

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Share to Cell Nucleus
Share to Chromosomes, Fungal
Share to DNA, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Replication

Share to Electrophoresis, Gel, Two-Dimensional

Share to Regulatory Sequences, Nucleic Acid

Share to Replication Origin

Share to Transformation, Genetic

Source

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Identifiers

PMID: 21408151
DOI: 10.1371/journal.pone.0017235
PMCID: PMC3050842

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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