Article
The strictly aerobic yeast Yarrowia lipolytica tolerates loss of a mitochondrial DNA-packaging protein.
Eukaryotic cell - 1 Sept 2014
Bakkaiova Jana, Arata Kosuke, Matsunobu Miki, Ono Bungo, Aoki Tomoyo, Lajdova Dana, Nebohacova Martina, Nosek Jozef, Miyakawa Isamu, Tomaska Lubomir
Abstract excerpt
Mitochondrial DNA (mtDNA) is highly compacted into DNA-protein structures termed mitochondrial nucleoids (mt-nucleoids). The key mt-nucleoid components responsible for mtDNA condensation are HMG box-containing proteins such as mammalian mitochondrial transcription factor A (TFAM) and Abf2p of the yeast Saccharomyces cerevisiae. To gain insight into the function and organization of mt-nucleoids in strictly aerobic...
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