Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New disease gene location and high genetic heterogeneity in idiopathic scoliosis.

European journal of human genetics : EJHG - 1 Aug 2011

Edery Patrick, Margaritte-Jeannin Patricia, Biot Bernard, Labalme Audrey, Bernard Jean-Claude, Chastang Joëlle, Kassai Behrouz, Plais Marie-Helene, Moldovan Florina, Clerget-Darpoux Francoise

Abstract excerpt

Idiopathic scoliosis (IS) is a spine disorder of unknown origin with 1.5-3% prevalence in the general population. Besides the large multifactorial-form sample of IS, there is a good evidence for the existence of a monogenic subgroup in which the disease is inherited in a dominant manner. However, results from literature suggest a strong heterogeneity in the locations of the mutated genes. Using a high-resolution...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 3
Share to Chromosomes, Human, Pair 5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Heterogeneity

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Genotype

Share to Pedigree

Share to Scoliosis

Source

Open in PubMed Open full text

Identifiers

PMID: 21407261
DOI: 10.1038/ejhg.2011.31
PMCID: PMC3172921

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New disease gene location and high genetic heterogeneity in idiopathic scoliosis.PMID 21407261Read ↗

Genetics and pathogenesis of idiopathic scoliosisSemantic proximity Read ↗

Genetic association of complex traits: using idiopathic scoliosis as an example.Semantic proximity Read ↗

Localization of susceptibility to familial idiopathic scoliosis.Semantic proximity Read ↗

Epidemiological survey of idiopathic scoliosis and sequence alignment analysis of multiple candidate genes.Semantic proximity Read ↗

The genetic epidemiology of idiopathic scoliosisSemantic proximity Read ↗

Spine update: genetics of familial idiopathic scoliosis.Semantic proximity Read ↗

Candidate gene analysis and exome sequencing confirm LBX1 as a susceptibility gene for idiopathic scoliosis.Semantic proximity Read ↗

Whole Genome Sequencing in Adolescent Idiopathic Scoliosis Cohort Indicates Polygenic Disease Involving Multiple Biological PathwaysSemantic proximity Read ↗

Assignment of a locus for autosomal dominant idiopathic scoliosis (IS) to human chromosome 17p11.Semantic proximity Read ↗

Genetics of familial idiopathic scoliosis.Semantic proximity Read ↗

Functional variants of POC5 identified in patients with idiopathic scoliosis.Semantic proximity Read ↗

A polygenic burden of rare variants across extracellular matrix genes among individuals with adolescent idiopathic scoliosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.