Article
Localization of susceptibility to familial idiopathic scoliosis.
Spine - 15 Sept 2000
Wise C A, Barnes R, Gillum J, Herring J A, Bowcock A M, Lovett M
Abstract excerpt
STUDY DESIGN: Genome-wide linkage surveys in large multiplex families with apparent inherited idiopathic scoliosis. OBJECTIVE: To identify chromosomal loci encoding genes involved in susceptibility to idiopathic scoliosis by positional cloning. SUMMARY OF BACKGROUND DATA: Although the inheritance of idiopathic scoliosis most often exhibits a complex pattern, autosomal dominant inheritance can be identified in...
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