Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A20 (TNFAIP3) genetic alterations in EBV-associated AIDS-related lymphoma.

Blood - 5 May 2011

Giulino Lisa, Mathew Susan, Ballon Gianna, Chadburn Amy, Barouk Sharon, Antonicelli Giuseppina, Leoncini Lorenzo, Liu Yi Fang, Gogineni Swarna, Tam Wayne, Cesarman Ethel

Abstract excerpt

A20, a negative regulator of NF-κB, has been implicated as a tumor suppressor gene in multiple types of B-cell lymphoma. AIDS-related lymphomas (ARLs) are high-grade B-cell lymphomas that are frequently associated with EBV infection. We examined a panel of ARLs for A20 alterations. FISH showed A20 deletion in 6 of 33 cases (18%). A20 mutations were found in 3 of 19 cases (16%), including 2 cases with deletions of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epstein-Barr Virus Infections
Share to Gene Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Silencing

Share to In Situ Hybridization, Fluorescence

Share to Intracellular Signaling Peptides and Proteins

Share to NF-kappa B

Share to Tumor Necrosis Factor alpha-Induced Protein 3

Share to Viral Matrix Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21406721
DOI: 10.1182/blood-2010-10-310995
PMCID: PMC3100694

Genes

TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A20 (TNFAIP3) genetic alterations in EBV-associated AIDS-related lymphoma.PMID 21406721Read ↗

A novel A20 (TNFAIP3) antibody (Ber-A20) can be used to detect unmutated A20 by immunohistology.Semantic proximity Read ↗

TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas.Semantic proximity Read ↗

Genetic relationships between A20/TNFAIP3, chronic inflammation and autoimmune disease.Semantic proximity Read ↗

A20 inactivation in ocular adnexal MALT lymphomaSemantic proximity Read ↗

Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.Semantic proximity Read ↗

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma.Semantic proximity Read ↗

A20 (TNFAIP3) Alterations in Primary Intestinal Diffuse Large B-cell Lymphoma.Semantic proximity Read ↗

The NF-{kappa}B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas.Semantic proximity Read ↗

A20 in inflammation and autoimmunity.Semantic proximity Read ↗

Frequent inactivation of A20 in B-cell lymphomasSemantic proximity Read ↗

Mutation analysis of the TNFAIP3 (A20) tumor suppressor gene in CLL.Semantic proximity Read ↗

A20 takes on tumors: tumor suppression by an ubiquitin-editing enzyme.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.