Article
Association of HSP70 and its co-chaperones with Alzheimer's disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2011
Broer Linda, Ikram Mohammad Arfan, Schuur Maaike, DeStefano Anita L, Bis Joshua C, Liu Fan, Rivadeneira Fernando, Uitterlinden Andre G, Beiser Alexa S, Longstreth William T, Hofman Albert, Aulchenko Yurii, Seshadri Sudha, Fitzpatrick Annette L, Oostra Ben A, Breteler Monique M B, van Duijn Cornelia M
Abstract excerpt
The heat shock protein (HSP) 70 family has been implicated in the pathology of Alzheimer's disease (AD). In this study, we examined common genetic variations in the 80 genes encoding HSP70 and its co-chaperones. We conducted a study in a series of 462 patients and 5238 unaffected participants der...
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