Article
Drosophila Ajuba is not an Aurora-A activator but is required to maintain Aurora-A at the centrosome.
Journal of cell science - 1 Apr 2011
Sabino Dora, Brown Nicholas H, Basto Renata
Abstract excerpt
The LIM-domain protein Ajuba localizes at sites of epithelial cell-cell adhesion and has also been implicated in the activation of Aurora-A (Aur-A). Despite the expected importance of Ajuba, Ajuba-deficient mice are viable, which has been attributed to functional redundancy with the related LIM-domain protein LIMD1. To gain insights into the function of Ajuba, we investigated its role in Drosophila, where a...
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