Article
Osteoarthritis susceptibility genes influence the association between hip morphology and osteoarthritis.
Arthritis and rheumatism - 1 May 2011
Waarsing J H, Kloppenburg M, Slagboom P E, Kroon H M, Houwing-Duistermaat J J, Weinans H, Meulenbelt I
Abstract excerpt
OBJECTIVE: The identified osteoarthritis (OA) susceptibility genes are mainly active in skeletal development and could thus affect joint geometry. Because nonoptimal joint geometry is a risk factor for the development of OA, we investigated if and how the path that leads from nonoptimal joint geometry to OA of the hip is influenced by these genes. METHODS: The shape of the hips of subjects in the Genetics,...
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