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Article

Variant alleles of the Wnt antagonist FRZB are determinants of hip shape and modify the relationship between hip shape and osteoarthritis.

Arthritis and rheumatism - 1 May 2012

Baker-Lepain Julie C, Lynch John A, Parimi Neeta, McCulloch Charles E, Nevitt Michael C, Corr Maripat, Lane Nancy E

Abstract excerpt

OBJECTIVE: To test whether single-nucleotide polymorphisms (SNPs) of the FRZB gene are associated with hip shape, and to determine whether FRZB variant alleles affect the relationship between hip shape and radiographic osteoarthritis (OA) of the hip. METHODS: A nested case-control study of Caucasian women, age ≥65 years, from the Study of Osteoporotic Fractures cohort was performed. Cases (n = 451) were defined...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Intracellular Signaling Peptides and Proteins

Share to Osteoarthritis, Hip

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Source

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Identifiers

PMID: 22544526
DOI: 10.1002/art.34526
PMCID: PMC3340442

Genes

FRZB

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