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Article

A two-gene balance regulates Salmonella typhimurium tolerance in the nematode Caenorhabditis elegans.

PloS one - 2 Mar 2011

Marsh Elizabeth K, van den Berg Maaike C W, May Robin C

Abstract excerpt

Lysozymes are antimicrobial enzymes that perform a critical role in resisting infection in a wide-range of eukaryotes. However, using the nematode Caenorhabditis elegans as a model host we now demonstrate that deletion of the protist type lysozyme LYS-7 renders animals susceptible to killing by the fatal fungal human pathogen Cryptococcus neoformans, but, remarkably, enhances tolerance to the enteric bacteria...

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Source

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Identifiers

PMID: 21399680
DOI: 10.1371/journal.pone.0016839
PMCID: PMC3047536

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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