Article
A conserved Toll-like receptor is required for Caenorhabditis elegans innate immunity.
EMBO reports - 1 Jan 2008
Tenor Jennifer L, Aballay Alejandro
Abstract excerpt
Pathogen recognition through Toll-like receptors (TLRs) is crucial in order to mount an appropriate immune response against microorganisms. On the basis of a lack of evidence indicating that Caenorhabditis elegans uses TLRs to elicit an immune response and on the absence of genes encoding Rel-like transcription factors in its genome, it is believed that TLR-mediated immunity arose after coelomates split from...
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