Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains.

doi:10.1128/JVI.64.4.1556-1565.1990

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Article

Promoter-specific trans activation and repression by human cytomegalovirus immediate-early proteins involves common and unique protein domains.

Journal of virology - 1 Apr 1990

Stenberg R M, Fortney J, Barlow S W, Magrane B P, Nelson J A, Ghazal P

Abstract excerpt

trans activation of promoters by viral regulatory proteins provides a useful tool to study coordinate control of gene expression. Immediate-early (IE) regions 1 and 2 of human cytomegalovirus (CMV) code for a series of proteins that originate from differentially spliced mRNAs. These IE proteins a...

Topics

Base Sequence
Cytomegalovirus
DNA, Viral
Humans
Models, Genetic
Molecular Sequence Data
Molecular Weight
Mutation
Plasmids
Promoter Regions, Genetic
Repressor Proteins
Structure-Activity Relationship
Transcription Factors
Transcriptional Activation
Transfection

Source

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Identifiers

PMID: 2157043
DOI: 10.1128/JVI.64.4.1556-1565.1990
PMCID: PMC249290

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2157043-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Viral Regulatory and Accessory Proteins