Article
G72 gene is associated with susceptibility to methamphetamine psychosis.
Progress in neuro-psychopharmacology & biological psychiatry - 31 Aug 2009
Kotaka Tatsuya, Ujike Hiroshi, Okahisa Yuko, Takaki Manabu, Nakata Kenji, Kodama Masafumi, Inada Toshiya, Yamada Mitsuhiko, Uchimura Naohisa, Iwata Nakao, Sora Ichiro, Iyo Masaomi, Ozaki Norio, Kuroda Shigetoshi
Abstract excerpt
Methamphetamine psychosis is considered as one of the pharmacological models of schizophrenia, and a hyperdopaminergic one. However, many lines of experimental evidence indicate that glutamatergic signaling is also involved in development of methamphetamine psychosis. Several genes related to glutamate function, e.g. the DTNBP1, G72, and GRM3 genes, were shown to be associated with schizophrenia susceptibility....
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