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Article

Steroid combination therapy and detoxification enzyme gene polymorphisms in sudden sensorineural hearing loss patients.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology - 1 Jul 2011

Um Jae-Young, Jang Chul-Ho, Kim Su-Jin, Kim Hye-Lin, Kim Seon-Young, Cho Young-Bum, Hong Seung-Heon

Abstract excerpt

OBJECTIVE: The purpose of this study was to evaluate the relations among the combined therapy with steroid and the detoxification enzyme gene polymorphisms in patients with sudden sensorineural hearing loss (SSNHL). The pathogenetic mechanism of inner ear dysfunction could involve an increase in lipid peroxidation and a decrease in cellular antioxidant defense. Glutathione S-transferases (GSTs) and cytochrome...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21389901
DOI: 10.1097/MAO.0b013e31821341ac

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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