Article
Decreased disulphide/thiol ratio in patients with autosomal recessive non-syndromic hearing loss.
International journal of pediatric otorhinolaryngology - 1 Sept 2018
Balta Burhan, Gundogdu Ramazan, Erdogan Murat, Alisik Murat, Kiraz Aslihan, Ozcan Ibrahim, Erel Ozcan
Abstract excerpt
INTRODUCTION: Oxidative stress plays a key role in the formation of age-related, noise-induced and drug-induced hearing loss. Thiols are organic compounds which can react with free radicals to protect against tissue and cell damage caused by reactive oxygen. There are no studies in literature on the association between autosomal recessive non-syndromic hearing loss(ARNSHL) including GJB2 and non-GJB2 mutations...
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