Association between the methylenetetrahydrofolate reductase gene C677T polymorphism and sudden sensorineural hearing loss: a meta-analysis.

doi:10.1007/s00405-014-3198-9

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Article

Association between the methylenetetrahydrofolate reductase gene C677T polymorphism and sudden sensorineural hearing loss: a meta-analysis.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery - 1 Sept 2015

Shu Jingcheng, Yin Shihua, Tan An-Zhou, He Meirong

Abstract excerpt

A variety of epidemiological studies have evaluated the association between methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism and sudden sensorineural hearing loss (SSNHL), but the results were inconsistent. The aim of this meta-analysis was to clarify more accurately the associ...

Topics

Genetic Predisposition to Disease
Hearing Loss, Sensorineural
Hearing Loss, Sudden
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Polymorphism, Genetic
White People

Source

Open in PubMed

Identifiers

PMID: 25012704
DOI: 10.1007/s00405-014-3198-9

Genes

POR
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-25012704-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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