Article
Glutathione S-transferase M1, T1, and P1 polymorphisms as susceptibility factors for noise-induced temporary threshold shift.
Hearing research - 1 Nov 2009
Lin Cheng-Yu, Wu Jiunn-Liang, Shih Tung-Sheng, Tsai Perng-Jy, Sun Yih-Min, Guo Yueliang Leon
Abstract excerpt
The generation of reactive oxygen species (ROS) is thought to be part of the mechanism underlying noise-induced hearing loss (NIHL). Glutathione is an important cellular antioxidant that limits cell damage by ROS. We aimed to determine the effect of genetic polymorphisms of glutathione S-transfer...
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