Article
Transcription of a yeast phosphoglucomutase isozyme gene is galactose inducible and glucose repressible.
Molecular and cellular biology - 1 Apr 1990
Oh D, Hopper J E
Abstract excerpt
The Saccharomyces cerevisiae GAL5 (PGM2) gene was isolated and shown to encode the major isozyme of phosphoglucomutase. Northern (RNA) blot hybridization revealed that the GAL5 transcript level increased three- to fourfold in response to galactose and was severely repressed in response to glucose...
Topics
- Cloning, Molecular
- Enzyme Induction
- Enzyme Repression
- Escherichia coli
- Galactose
- Genes, Fungal
- Genetic Complementation Test
- Genotype
- Glucose
- Isoenzymes
- Mutation
- Phosphoglucomutase
- Plasmids
- Restriction Mapping
- Saccharomyces cerevisiae
- Transcription, Genetic