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Article

Analysis of the GAL3 signal transduction pathway activating GAL4 protein-dependent transcription in Saccharomyces cerevisiae.

Genetics - 1 Jun 1990

Bhat P J, Oh D, Hopper J E

Abstract excerpt

The Saccharomyces cerevisiae GAL/MEL regulon genes are normally induced within minutes of galactose addition, but gal3 mutants exhibit a 3-5-day induction lag. We have discovered that this long-term adaptation (LTA) phenotype conferred by gal3 is complemented by multiple copies of the GAL1 gene. Based on this result and the striking similarity between the GAL3 and GAL1 protein sequences we attempted to detect...

Topics

Blotting, Southern
Blotting, Western
Galactokinase
Galactose
Galactosidases
Genes, Fungal
Genes, Regulator
Kinetics
Melibiose
Phenotype
Restriction Mapping
Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Signal Transduction

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 2199310
DOI: 10.1093/genetics/125.2.281
PMCID: PMC1204018

Genes

LTA
GAL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2199310-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Analysis of the GAL3 signal transduction pathway activating GAL4 protein-dependent transcription in Saccharomyces cerevisiae.PMID 2199310Read ↗

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Transcriptional control of the GAL/MEL regulon of yeast Saccharomyces cerevisiae: mechanism of galactose-mediated signal transduction.Semantic proximity Read ↗

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