Article
Developmental and metabolic regulation of the phosphoglucomutase-encoding gene, pgmB, of Aspergillus nidulans.
Molecular & general genetics : MGG - 1 Jan 2000
Hoffmann B, LaPaglia S K, Kübler E, Andermann M, Eckert S E, Braus G H
Abstract excerpt
We have isolated the pgmB gene from Aspergillus nidulans, which encodes a phosphoglucomutase, one of the key enzymes in carbohydrate metabolism. The pgmB gene is located on chromosome VII and its ORF encodes 557 amino acids. Mutant phenotypes were analysed by expression of high levels of pgmB antisense RNA, which lead to a loss of detectable levels of sense RNA. Under conditions of antisense RNA expression, a 30%...
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