Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preferred apical distribution of glycosyl-phosphatidylinositol (GPI) anchored proteins: a highly conserved feature of the polarized epithelial cell phenotype.

The Journal of membrane biology - 1 Feb 1990

Lisanti M P, Le Bivic A, Saltiel A R, Rodriguez-Boulan E

Abstract excerpt

We use a sensitive biotin polarity assay to survey the surface distribution of glycosyl-phosphatidylinositol (GPI) anchored proteins in five model epithelial cell lines derived from different species (dog, pig, man) and tissues, i.e., kidney (MDCK I, MDCK II, LLC-PK1) and intestine (Caco-2 and SK-CO15). After biotinylation of apical or basolateral surfaces of confluent monolayers grown on polycarbonate filters,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line
Share to Dogs

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epithelium

Share to Immunoblotting

Share to Intestinal Mucosa

Share to Kidney

Share to Membrane Proteins

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 2138677
DOI: 10.1007/BF01872889
PMCID: PMC7087518

Genes

GPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preferred apical distribution of glycosyl-phosphatidylinositol (GPI) anchored proteins: a highly conserved feature of the polarized epithelial cell phenotype.PMID 2138677Read ↗

Polarized traffic towards the cell surface: how to find the routeSemantic proximity Read ↗

Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cells.Semantic proximity Read ↗

Selective control of basolateral membrane protein polarity by cdc42.Semantic proximity Read ↗

Developmental regulation of membrane protein sorting in Drosophila embryos.Semantic proximity Read ↗

Plasma membrane protein sorting in polarized epithelial cells.Semantic proximity Read ↗

AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells.Semantic proximity Read ↗

Rab14 regulates apical targeting in polarized epithelial cells.Semantic proximity Read ↗

Loss of galectin-3 impairs membrane polarisation of mouse enterocytes in vivo.Semantic proximity Read ↗

N- and O-glycans are not directly involved in the oligomerization and apical sorting of GPI proteins.Semantic proximity Read ↗

Identification of a cytoplasmic signal for apical transcytosis.Semantic proximity Read ↗

Galectin-4-mediated transcytosis of transferrin receptor.Semantic proximity Read ↗

Mannosamine, a novel inhibitor of glycosylphosphatidylinositol incorporation into proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.