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Article

Loss of putzig Activity Results in Apoptosis during Wing Imaginal Development in Drosophila.

PloS one - 1 Jan 2015

Zimmermann Mirjam, Kugler Sabrina J, Schulz Adriana, Nagel Anja C

Abstract excerpt

The Drosophila gene putzig (pzg) encodes a nuclear protein that is an integral component of the Trf2/Dref complex involved in the transcription of proliferation-related genes. Moreover, Pzg is found in a complex together with the nucleosome remodeling factor NURF, where it promotes Notch target gene activation. Here we show that downregulation of pzg activity in the developing wing imaginal discs induces an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25894556
DOI: 10.1371/journal.pone.0124652
PMCID: PMC4403878

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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