KAR3, a kinesin-related gene required for yeast nuclear fusion.

doi:10.1016/0092-8674(90)90351-e

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Article

KAR3, a kinesin-related gene required for yeast nuclear fusion.

Cell - 23 Mar 1990

Meluh P B, Rose M D

Abstract excerpt

The KAR3 gene is essential for yeast nuclear fusion during mating, and its expression is strongly induced by alpha factor. The predicted KAR3 protein sequence contains two globular domains separated by an alpha-helical coiled coil. The carboxy-terminal domain is homologous to the amino-terminal mechanochemical domain of Drosophila kinesin heavy chain. Mutation of the putative ATP binding site produces a dominant...

Topics

Adenosine Triphosphatases
Adenosine Triphosphate
Amino Acid Sequence
Base Sequence
Binding Sites
Cell Nucleus
Fungal Proteins
Genes, Fungal
Genetic Complementation Test
Genotype
Kinesins
Microtubule-Associated Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Phenotype

Plasmids

Protein Conformation

RNA, Messenger

Source

Open in PubMed

Identifiers

PMID: 2138512
DOI: 10.1016/0092-8674(90)90351-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2138512-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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