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Article

KAR3, a kinesin-related gene required for yeast nuclear fusion.

Cell - 23 Mar 1990

Meluh P B, Rose M D

Abstract excerpt

The KAR3 gene is essential for yeast nuclear fusion during mating, and its expression is strongly induced by alpha factor. The predicted KAR3 protein sequence contains two globular domains separated by an alpha-helical coiled coil. The carboxy-terminal domain is homologous to the amino-terminal mechanochemical domain of Drosophila kinesin heavy chain. Mutation of the putative ATP binding site produces a dominant...

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PMID: 2138512
DOI: 10.1016/0092-8674(90)90351-e

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Click a neighbor to travelStep 1 · 12 closest

KAR3, a kinesin-related gene required for yeast nuclear fusion.PMID 2138512Read ↗

Microtubule motor protein Kar3 is required for normal mitotic division and morphogenesis in Candida albicans.Semantic proximity Read ↗

pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.Semantic proximity Read ↗

Loss of function of Saccharomyces cerevisiae kinesin-related CIN8 and KIP1 is suppressed by KAR3 motor domain mutations.Semantic proximity Read ↗

Separate domains of KAR1 mediate distinct functions in mitosis and nuclear fusion.Semantic proximity Read ↗

A mutation of the fission yeast EB1 overcomes negative regulation by phosphorylation and stabilizes microtubules.Semantic proximity Read ↗

Distinct roles for key karyogamy proteins during yeast nuclear fusion.Semantic proximity Read ↗

The Wiskott-Aldrich syndrome protein (WASP) is essential for myoblast fusion in Drosophila.Semantic proximity Read ↗

Mitotic motors in Saccharomyces cerevisiae.Semantic proximity Read ↗

Kinesin-related KIP3 of Saccharomyces cerevisiae is required for a distinct step in nuclear migration.Semantic proximity Read ↗

Genetic interactions between KAR7/SEC71, KAR8/JEM1, KAR5, and KAR2 during nuclear fusion in Saccharomyces cerevisiae.Semantic proximity Read ↗

The yeast motor protein, Kar3p, is essential for meiosis I.Semantic proximity Read ↗

ER membrane protein complex required for nuclear fusion.Semantic proximity Read ↗

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