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Article

Microtubule motor protein Kar3 is required for normal mitotic division and morphogenesis in Candida albicans.

Eukaryotic cell - 1 Sept 2008

Sherwood Racquel Kim, Bennett Richard J

Abstract excerpt

The kinesin-related protein Kar3 is a minus end-directed molecular motor that plays a multifunctional role in microtubule-directed nuclear movement. Previously, it was shown that Candida albicans Kar3p is critical for nuclear fusion during mating as kar3 mutants were defective in karyogamy. In this study, we confirm that Kar3p is required for nuclear congression in mating but that neither Kar3p nor the dynein...

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Identifiers

PMID: 18586948
DOI: 10.1128/EC.00138-08
PMCID: PMC2547067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Microtubule motor protein Kar3 is required for normal mitotic division and morphogenesis in Candida albicans.PMID 18586948Read ↗

The Saccharomyces cerevisiae kinesin-related motor Kar3p acts at preanaphase spindle poles to limit the number and length of cytoplasmic microtubules.Semantic proximity Read ↗

The Kar3-interacting protein Cik1p plays a critical role in passage through meiosis I in Saccharomyces cerevisiae.Semantic proximity Read ↗

Two related kinesins, klp5+ and klp6+, foster microtubule disassembly and are required for meiosis in fission yeast.Semantic proximity Read ↗

The Kip3-like kinesin KipB moves along microtubules and determines spindle position during synchronized mitoses in Aspergillus nidulans hyphae.Semantic proximity Read ↗

Kinesin-related KIP3 of Saccharomyces cerevisiae is required for a distinct step in nuclear migration.Semantic proximity Read ↗

Localization of the Kar3 kinesin heavy chain-related protein requires the Cik1 interacting protein.Semantic proximity Read ↗

The yeast motor protein, Kar3p, is essential for meiosis I.Semantic proximity Read ↗

Differential regulation of the Kar3p kinesin-related protein by two associated proteins, Cik1p and Vik1p.Semantic proximity Read ↗

pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.Semantic proximity Read ↗

KAR3, a kinesin-related gene required for yeast nuclear fusion.Semantic proximity Read ↗

Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins.Semantic proximity Read ↗

Kip3, the yeast kinesin-8, is required for clustering of kinetochores at metaphase.Semantic proximity Read ↗

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