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Article

Correlated evolution of nearby residues in Drosophilid proteins.

PLoS genetics - 1 Feb 2011

Callahan Benjamin, Neher Richard A, Bachtrog Doris, Andolfatto Peter, Shraiman Boris I

Abstract excerpt

Here we investigate the correlations between coding sequence substitutions as a function of their separation along the protein sequence. We consider both substitutions between the reference genomes of several Drosophilids as well as polymorphisms in a population sample of Zimbabwean Drosophila melanogaster. We find that amino acid substitutions are "clustered" along the protein sequence, that is, the frequency of...

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Identifiers

PMID: 21383965
DOI: 10.1371/journal.pgen.1001315
PMCID: PMC3044683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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