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Article

Longitudinal study of primary HIV-1 isolates in drug-naïve individuals reveals the emergence of variants sensitive to anti-HIV-1 monoclonal antibodies.

PloS one - 23 Feb 2011

Haldar Bijayesh, Burda Sherri, Williams Constance, Heyndrickx Leo, Vanham Guido, Gorny Miroslaw K, Nyambi Phillipe

Abstract excerpt

To study how virus evolution affects neutralization sensitivity and to determine changes that occur in and around epitopes, we tested the ability of 13 anti-HIV-1 gp120 (anti-V2, anti-V3, anti-CD4bd and anti-carbohydrate) human monoclonal antibodies (mAbs) to neutralize sequential viruses obtained from five HIV-1 chronically infected drug naïve individuals. Overall, primary viruses collected from patients at...

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Source

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Identifiers

PMID: 21383841
DOI: 10.1371/journal.pone.0017253
PMCID: PMC3044167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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