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Article

Epitope mapping of broadly neutralizing HIV-2 human monoclonal antibodies.

Journal of virology - 1 Nov 2012

Kong Rui, Li Hui, Georgiev Ivelin, Changela Anita, Bibollet-Ruche Frederic, Decker Julie M, Rowland-Jones Sarah L, Jaye Assan, Guan Yongjun, Lewis George K, Langedijk Johannes P M, Hahn Beatrice H, Kwong Peter D, Robinson James E, Shaw George M

Abstract excerpt

Recent studies have shown that natural infection by HIV-2 leads to the elicitation of high titers of broadly neutralizing antibodies (NAbs) against primary HIV-2 strains (T. I. de Silva, et al., J. Virol. 86:930-946, 2012; R. Kong, et al., J. Virol. 86:947-960, 2012; G. Ozkaya Sahin, et al., J. Virol. 86:961-971, 2012). Here, we describe the envelope (Env) binding and neutralization properties of 15 anti-HIV-2...

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Identifiers

PMID: 22933274
DOI: 10.1128/JVI.01632-12
PMCID: PMC3486499

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